Kallyope, which offers a drug-discovery platform focused on developing therapies involving the gut-brain axis, announced it had raised $236 million in a Series D funding round led by Mubadala Investment Company and the Column Group.

Other participants in the round include Alexandria Venture Investments, Bill Gates, Casdin Capital, Euclidean Capital, Illumina Ventures, Lux Capital, Polaris Partners, Two Sigma Ventures, StepStone Group, DNS Capital, Hartford Healthcare Endowment, Parkwood LLC and Tao Capital. The company said it has now raised nearly $480 million.

Kallyope plans to use the new investment to improve its platform, fund clinical trials and advance its therapy pipeline.

Direct-to-consumer virtual care company Ro scored $150 million in funding. The round was led by ShawSpring Partners, with participation from General Catalyst, FirstMark Capital, TQ Ventures, SignalFire, BoxGroup, the Chernin Group, Initialized Capital, Altimeter Capital, Baupost Group and Seven Seven Six.

"With this funding, Ro can accelerate our pursuit of revolutionizing healthcare by building accessible, impactful and trusted care that people want. This year, that means debuting a unified, single-branded care experience for our patients and further enabling other healthcare companies to benefit from the patient-centric technology and services we've built," Ro cofounder and CEO Zachariah Reitano said in a statement.

The company also announced the launch of Ro Derm, a digital skincare clinic. Last year, Ro raised $500 million and acquired Modern Fertility and at-home diagnostic company Kit.

Memora Health, a platform for managing complex care needs including messaging, automated reminders, metrics and scheduling, scooped up $40 million.

The round was led by Transformation Capital, with participation from investors including Andreessen Horowitz, Frist Cressey Ventures, Edward Elmhurst Health and AlleyCorp. According to Crunchnbase, the investment brings the company's total raise to $50.5 million. 

"Memora solves one of the most pressing issues for providers – automating complex care journeys where patient touchpoints are key for better outcomes, and caregivers can collaboratively manage these care journeys and monitor their progress," Todd Cozzens, managing partner at Transformation Capital, said in a statement. He will join Memora's board as part of the investment.

"Memora has built an integrated platform with a growing library of hundreds of journeys across all major specialties, and is digitizing the best care-management process for complex patients from leading health systems. The result is a user-friendly tool for patients and caregivers to manage complex care in a systematic and consistent way."

Digital fitness company FitOn scored $40 million in a Series C funding round led by Delta-v Capital.

Accel, Maverick Ventures, Second Avenue Partners and Mantis VC also participated, along with a strategic investment from UTA VC, United Talent Agency's venture arm. The Series C comes months after an $18 million round announced in October, bringing the fitness startup's total raise to $70 million.

Along with the investment, FitOn also announced the acquisition of Peerfit, a fitness company focused on the employer market. 

"Given the new normal of hybrid and remote work, we believe – now more than ever – that it is critical to create accessible, personalized health and fitness solutions," FitOn cofounder and CEO Lindsay Cook said in a statement.

"FitOn is laser-focused on positive social engagement among consumers, employees and plan members, providing them with fun and exciting ways to get fit, de-stress, and connect with each other. Combining Peerfit with the innovative digital platform we have built at FitOn, will create a first-of-its-kind virtual and in-person wellness experience to engage people both at home and in their communities."

Healthcare staffing startup Kevala raised $12.1 million in Series A funding. 

The round was led by Cercano Management, with participation from Costanoa Ventures, High Alpha and PSL Ventures. The company scored $4 million in seed funding early last year. 

Initially focused on long-term care staffing, scheduling and credentialing, Kevala plans to expand into new states this year. It currently operates in Washington, Oregon, Utah, Montana and Texas.

"The staffing crisis has made it difficult, if not impossible, for schedulers to keep shifts full, compliant and productive," Kevala cofounder and CEO Todd Owens said in a statement. "Healthcare operators, stretched thin and unable to rely on permanent staff alone, are looking for more flexible staffing options, including agency and internal float teams."